在患有心房的患者中,休息和压力导致左心房功能障碍
Angela Zagatina1, Maria Rivadeneira Ruiz2, Quirino Ciampi3
1Cardiology Department, Research Scientific Cardiocenter "Medika", 197110 St. Petersburg, Russia.
Journal of clinical medicine
|September 28, 2023
概括
左心房扩张和功能障碍在与心房动 (AF) 相关的慢性冠状动脉综合征中很常见,随着AF的严重程度而恶化. 压力心声扫描揭示了这些问题,将它们与增加的肺堵塞联系起来.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 耳前的研究研究研究.
背景情况:
- 左心房 (LA) 肌病症在慢性冠状动脉综合征 (CCS) 与心房动 (AF) 中很常见.
- 在休息状态下,LA功能障碍可能是隐藏的,在压力时才会显现出来.
- 了解CCS-AF中的LA变化对于风险分层至关重要.
研究的目的:
- 评估慢性冠状动脉综合征 (CCS) 患者在休息和压力期间的左心房 (LA) 体积和功能.
- 为了评估这些参数在整个心房的频谱 (AF),从鼻节奏到永久的AF.
- 为了将LA变化与诱导性缺血和肺堵塞在应力心声图期间相关联.
主要方法:
- 对3042名已知或怀疑患有CCS的患者进行了前性多中心观察研究.
- 患者被分为鼻腔节律 (SR),SR与先前的阳性肌痛,和永久性肌痛组.
- 进行压力回声心电图 (SE),测量左心房体积指数 (LAVI) 和 LA 应变储阶段 (LASr).
主要成果:
- 左心房体积指数 (LAVI) 从SR显著增加到永久的AF组,无论是在休息状态还是应激状态.
- 在整个AF频谱中,拉氏菌株储存阶段 (LASr) 逐渐下降,表明功能受损.
- 压力诱导的B线 (肺堵塞) 和可诱导性缺血在AF患者中更为频繁.
结论:
- 休息和压力左心房扩张和储功能障碍在CCS患者中普遍存在,特别是永久性AF.
- 这些LA异常与压力期间诱导性缺血和肺堵塞的增加有关.
- 压力心声图对于检测CCS-AF患者隐藏的LA功能障碍非常有价值.
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