在患有糖尿病和胃肠道症状的受试者中,基于MRI的全食功能和运动量的量化
Davide Bertoli1,2, Esben Bolvig Mark1, Donghua Liao1
1Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, 9000 Aalborg, Denmark.
Journal of clinical medicine
|September 28, 2023
概括
磁共振成像揭示了糖尿病和胃肠道症状患者的胃肠道结构和功能差异. 这些发现有助于诊断和管理这些常见的,具有挑战性的疾病.
科学领域:
- 胃肠病学 胃肠病学
- 医疗成像医学成像
- 内分泌学 在内分泌学.
背景情况:
- 胃肠道 (GI) 症状在糖尿病中很普遍,但难以诊断和管理.
- 多段磁共振成像 (MRI) 提供了一种非侵入性方法来评估肠道结构和功能.
研究的目的:
- 用MRI评估糖尿病患者的胃肠道结构和功能参数,患者有胃肠道症状.
- 探索这些参数与患者报告的症状之间的关联.
- 使用机器学习识别区分糖尿病患者与健康对照患者的特征.
主要方法:
- 86名参与者 (46名患有糖尿病和胃肠道症状,40名健康对照) 接受了基线和饭后的MRI扫描.
- 收集的数据包括胃,小肠和结肠的体积和机动性.
- 调查问卷评估了症状严重程度和与成像发现的关联.
主要成果:
- 与对照组相比,糖尿病患者的胃和小肠体积较大,结肠体积较小.
- 患者在食后表现出小肠机动性降低.
- 在胃体积和腹度,胃排空时间和反流以及小肠运动和便秘之间发现了积极的关联.
结论:
- 糖尿病和胃肠道症状患者存在显著的结构和功能性胃肠道差异,包括改变体积和减少小肠动性.
- 这些发现与患者的症状体验相关.
- 使用小肠体积和运动率的机器学习模型在将患者与对照区分时取得了76%的准确性.
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