生活方式,左心房结构和功能,以及代谢综合征成年人的认知衰退
Ines Gonzalez Casanova1, Ángel M Alonso-Gómez2,3, Dora Romaguera3,4
1Department of Applied Health Science, School of Public Health, Indiana University Bloomington, Bloomington, IN 47404, USA.
Journal of clinical medicine
|September 28, 2023
概括
这项研究没有发现任何证据表明左心房结构或功能调解了超重或肥胖成年人的生活方式因素 (饮食,运动,体重) 和认知功能之间的联系. 需要对更大样本进行进一步的研究.
科学领域:
- 心脏病学 心脏病学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 饮食和体育活动等生活方式因素与认知功能有关,但潜在的机制尚不清楚.
- 健康的生活方式与改善左心房结构和功能相关,这也与更好的认知表现有关.
- 研究心脏的作用,特别是左心房的特征,可能会揭示连接生活方式和认知的途径.
研究的目的:
- 测试左心房结构和功能是否调解生活方式因素 (地中海饮食,体育活动,体重) 和认知功能之间的关联.
- 探索潜在的心血管路径,将生活方式选择与超重/肥胖和代谢综合征患者的执行功能联系起来.
主要方法:
- 来自西班牙的476名超重/肥胖的参与者患有代谢综合征.
- 基线生活方式评估,胸前心声学和执行功能测试 (Trail Making A).
- 对认知功能的测量进行了为期两年的随访;进行了调解分析.
主要成果:
- 在生活方式因素 (遵守地中海饮食,身体活动,体重) 和Trail Making A测试成绩之间没有发现显著的关联.
- 左心房结构和功能的心声测量没有介绍生活方式因素和认知功能之间的关系.
- 该研究没有确定左心房特征作为生活方式-认知关联中介.
结论:
- 这项研究不支持左心房结构和功能作为生活方式和认知功能之间的调解者在这个队列.
- 适度的样本大小是一个局限性,表明需要进行更大的研究.
- 进一步的研究应该探索其他可能调解生活方式-认知关系的心血管因素.
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