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单胞胎双胞胎怀孕的周产期结果是通过自然方式怀孕,还是通过辅助生殖技术

Alicia Martínez-Varea¹, Martha Martínez-Gómez¹, Blanca Novillo¹

¹Department of Obstetrics and Gynaecology, La Fe University and Polytechnic Hospital, Avenida Fernando Abril Martorell 106, 46026 Valencia, Spain.

Journal of clinical medicine

|September 28, 2023

概括

通过辅助生殖技术 (ART) 怀孕的单胞胎双胞胎怀孕与自然怀孕的双胞胎相比,怀孕期糖尿病的风险更高. 其他妊娠并发症和新生儿结局在各组之间是相似的.

科学领域:

生殖医学生殖医学
孕产妇和胎儿医学孕产妇和胎儿医学
周围生理学周围生理学

背景情况:

通过辅助生殖技术 (ART) 怀孕的单胞胎双胞胎怀孕可能与自然怀孕的孕产期结果不同.
之前的报道表明,在ART受孕的单子双胞胎中,流产,剖腹产和新生儿死亡的风险增加.
了解这些差异对于优化高风险妊娠的护理至关重要.

研究的目的:

为了比较自然和通过ART怀孕的双胞胎怀孕之间的周产期结果.
在MCDA双胞胎中识别与ART怀孕相关的特定风险.

主要方法:

在第三级医院 (2015-2021) 的MCDA双胞胎怀孕的回顾性队列研究.
包括自然怀孕和ART怀孕的MCDA怀孕.
母亲特征,妊娠并发症,分娩方式和新生儿结果的比较.

主要成果:

在ART怀孕的MCDA怀孕中,母亲的年龄较大,零生育率更高.
在ART组中,妊娠糖尿病 (22.9%对2.7%) 和高血压疾病的发生率显著增加.
双胞胎对双胞胎输血综合征没有显著差异;自然受孕组的阴道分娩率更高.
调整后的分析显示,ART受孕与妊娠糖尿病独立相关 (aOR 7.86).

结论:

通过人工智能治疗怀孕的MCDA双胞胎怀孕患妊娠糖尿病的风险明显更高.
两组之间在其他妊娠并发症,分娩方式或新生儿结局方面没有发现显著差异.
在MCDA双胞胎中,ART怀孕是妊娠糖尿病的风险因素,因此需要有针对性的监测.

关键词:

辅助生殖技术是一种辅助生殖技术.双胞胎怀孕的双胞胎怀孕是一个单质的双胞胎怀孕.自然的概念是自然的概念.围产期的结果.双胞胎的怀孕双胞胎的怀孕

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