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在系统性硬化症患者中,周围血液CD21低 B细胞和血清IL-4和IL-21影响关节卷入

Chiara Pellicano1, Amalia Colalillo1, Valeria Carnazzo2

  • 1Department of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.

Journal of personalized medicine
|September 28, 2023
PubMed
概括

系统性硬化症患者较高的关节参与显示增加了CD21低 B细胞,IL-4和IL-21. 这些标记物独立地与更大的疾病活性有关,这表明它在SSc关节病原发生过程中发挥了作用.

关键词:
CD21 低 低 的在 DAS2828 中,您可以在 DAS28 中使用.它们是IL-21和IL-21.IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-4-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL-IL is is is is is what is what is what is what is what is what is what is关节炎是一种关节炎.一个共同的共同的共同的共同.系统性硬化症 系统性硬化症

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