东京指南与急性胆囊炎病理严重程度之间的关系
Tae Young Park1, Jae Hyuk Do2, Hyoung-Chul Oh2
1Division of Gastroenterology, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong 14353, Republic of Korea.
Journal of personalized medicine
|September 28, 2023
概括
根据东京指南对急性胆囊炎 (AC) 的严重程度分级与胆囊炎症没有相关性. 然而,较高的AC等级显示血液和胆汁中的积极微生物培养增加.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
- 传染性疾病 传染性疾病
背景情况:
- 急性胆囊炎 (AC) 的严重程度是根据东京指南 (TG) 进行分类的.
- AC严重程度,胆囊 (GB) 炎症程度和实验室发现之间的相关性仍然不清楚.
- 这项研究研究了AC严重程度 (TGs),GB组织病理学和实验室/微生物学数据之间的关系.
研究的目的:
- 根据东京指南,评估AC的严重程度是否与组织病理性GB炎症一致.
- 评估AC严重程度与实验室发现之间的相关性,包括血液和胆汁微生物培养.
- 确定TGs在反映AC中炎症和感染的真实程度方面的实用性.
主要方法:
- 对217名为AC进行胆囊切除术的患者进行了回顾性审查 (2017年1月 - 2020年5月).
- 人口统计数据,实验室结果,微生物培养 (血液/胆汁),GB炎症程度和基于TG严重程度等级 (I,II,III) 的石头组成的比较.
- 统计分析以确定严重程度组之间的显著差异.
主要成果:
- 在TG重度等级之间没有观察到胆囊炎症程度的显著差异.
- 较高的AC严重程度等级 (III与I/II) 与老年患者和实验室标记物 (WBC,CRP,肌素,白血素,血小板,白蛋白) 的显著变化有关.
- 血液和胆汁中的微生物隔离率在较高的AC严重程度 (p < 0.001) 时显著增加.
结论:
- 基于东京指南的AC严重程度与胰腺病理性胆囊炎症无关.
- 在血液和胆汁中增加的微生物隔离与更高的AC严重程度等级相对相关.
- 实验室发现和微生物学数据,而不是组织病理性炎症程度,似乎更能反映TGS定义的AC严重程度.
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