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药物遗传变异与Fluoxetine相关的药物动力学来自健康受试者的生物等价性研究

Carlos Alejandro Díaz-Tufinio1,2, José Antonio Palma-Aguirre2, Vanessa Gonzalez-Covarrubias3

  • 1Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City 14380, Mexico.

Journal of personalized medicine
|September 28, 2023
PubMed
概括

这项研究将fluoxetine药物反应的变异性与关键代谢基因 (如CYP2D6.6) 的遗传变异联系起来. 了解这些药物遗传学关联可以帮助个性化抗抑郁药物治疗,以获得更好的患者结果.

关键词:
生物等价性 生物等价性克塞提因 (fluoxetine) 是一种含有素的药物.基因型定制是基因型定制.代谢 代谢 代谢 代谢药物动力学 药物动力学

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