预测ERCP后胰腺炎 (PEP) 的预测因素 在Choledochal Lithiasis提取中使用
Adrian Boicean1,2, Victoria Birlutiu1,2, Cristian Ichim1,2
1County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.
Journal of personalized medicine
|September 28, 2023
概括
在女性中,ERCP后胰腺炎 (PEP) 的风险更高,并由高CRPR,TBIR和NLR预测. 较低的入院总胆红素水平也表明,在接受胆道结石ERCP的患者中,PEP风险增加.
科学领域:
- 胃肠病学 胃肠病学
- 内镜手术 进行内镜手术
- 胰腺学 胰腺学
背景情况:
- 在ERCP后的胰腺炎 (PEP) 是内镜逆向胆血管瘤造影 (ERCP) 的常见并发症.
- 预测PEP对于患者管理和优化ERCP程序至关重要.
研究的目的:
- 用人口统计数据和紧急血液检测值来确定ERCP后胰腺炎 (PEP) 的预测因子.
- 评估特定ERCP技术与PEP风险之间的关联.
主要方法:
- 对134名接受ERCP治疗的患者进行了回顾性分析.
- 用PEP和没有PEP的患者之间的人口统计和实验室数据的比较.
- 统计分析包括几率比率 (OR) 和置信区间 (CI) 来评估风险因素.
主要成果:
- 女性患PEP的风险增加 (OR: 2.893).
- 使用Dormia探针和扩张气球进行操纵,不放置胆管支架,降低了PEP风险 (OR:0.346).
- 在ERCP后增加的CRPR (OR: 4.337),TBIR (OR: 4.004) 和NLR (OR: 3.281) 是PEP的显著预测因素.
- 预测PEP的入院时较低的总 bilirubin 水平 (OR: 5.262).
结论:
- 人口因素和特定的ERCP技术影响PEP风险.
- 在ERCP后的某些血液测试比率和水平,以及入院胆红素,是PEP的有价值的预测指标.
- 这些发现可以帮助早期识别和管理患有PEP高风险的患者.
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