巴西大学人口的COVID-19疫苗接种和血清学概况
Marina Dos Santos Barreto1, Beatriz Soares da Silva1, Ronaldy Santana Santos1
1Department of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Life (Basel, Switzerland)
|September 28, 2023
概括
学术活动恢复,大多数参与者显示记忆免疫 (IgG) 和低最近感染指标 (IgM) 后COVID-19暂停. 对学术界来说,监测免疫力和更新疫苗仍然至关重要.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 高等教育 高等教育
背景情况:
- 由于COVID-19大流行,全球学术停课,影响数百万人.
- 恢复面对面的课程需要对学术人群的免疫状况进行评估.
研究的目的:
- 在巴西大学人口中评估IgM和IgG抗SARS-CoV-2抗体水平.
- 了解在长时间停课后恢复个人活动期间学术人员的免疫反应.
主要方法:
- 在巴西一所大学对942名参与者进行了五个月的横截面研究.
- 对抗SARS-CoV-2抗体的IgM和IgG的检测.
- 与疫苗接种状态,人口统计和感染史有关的抗体水平的分析.
主要成果:
- 大多数参与者表现出反应性IgG (记忆抗体) 和非反应性IgM (最近感染的标志物).
- 在接受了CoronaVac/ChAdOx1疫苗组合和完成疫苗接种计划的参与者中观察到更高的平均IgG水平.
- 老年参与者和那些与感染者接触的人显示出更高的IgM水平,没有基于性别,症状或先前感染的显著差异.
结论:
- 学术人口在很大程度上拥有回归面对面课程时的记忆免疫力,最近感染的迹象很小.
- 研究结果强调了在学术环境中持续免疫监测和及时更新疫苗接种的重要性.
- 这项研究提供了有关疫情后学术环境中的抗体患病率的宝贵数据.
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