大脑胎盘比率在识别高风险晚期怀孕中的效率
Raquel Martin-Alonso1,2, Valeria Rolle3,4, Ranjit Akolekar5,6
1Department of Obstetrics and Gynecology, Hospital Universitario de Torrejón, Torrejón de Ardoz, 28850 Madrid, Spain.
Medicina (Kaunas, Lithuania)
|September 28, 2023
概括
大脑胎盘比率 (CPR) 不能有效预测晚期怀孕中不良周产期结果. 这项研究发现,单独进行心肺复苏或与其他因素相结合,对识别风险妊娠的预测性能不佳.
科学领域:
- 围产儿医学 围产儿医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 产科 产科 产科 产科 产科
背景情况:
- 大脑胎盘比率 (CPR) 越来越多地被研究用于识别有不良结果风险的怀孕.
- 准确预测晚期怀孕中不良周产期结果仍然是一个临床挑战.
研究的目的:
- 评估CPR对40-42周妊娠不复杂单独怀孕中不良周产期结果的预测能力.
- 评估心肺复苏能否改善预测模型对晚期怀孕中不良周产期结果的预测.
主要方法:
- 在西班牙和英国 (2017-2019) 进行了3143例单独怀孕的回顾性队列研究.
- 确定的不良周产期结局包括死胎,新生儿死亡,紧急剖腹产/仪器分娩,低带血pH值,低Apgar评分和新生儿单位入院.
- 利用后勤混合模型和ROC曲线分析来评估预测性能.
主要成果:
- 孕产妇的年龄,BMI,种族,性别平等和产后诱导是不利结果的重要预测因素 (AUC 0.743).
- 将CPR添加到预测模型中并没有提高其性能.
- 当使用第10个百分点作为切线时,单独的CPR就具有较低的不良结果检测率 (11.9%).
结论:
- 在晚期,未经选择的怀孕中,心肺复苏术是不良预测周产期不良结果的不良预测.
- 目前的证据表明,心肺复苏不是一种可靠的查工具,用于识别高风险的妊娠.
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