益生菌补充剂在炎症中的可能作用:叙述性审查
Alessandro Colletti1,2, Marzia Pellizzato2, Arrigo Francesco Cicero3,4
1Department of Science and Drug Technology, University of Turin, 10124 Turin, Italy.
Microorganisms
|September 28, 2023
概括
肠道失调,肠道微生物的不平衡,可以导致炎症和疾病. 特定的益生菌菌株表现出抗炎作用,恢复肠道健康和eubiosis,特别是长期使用.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 肠道失生症涉及肠道微生物的不平衡,可能导致炎症和各种疾病.
- 这种不平衡会影响肠道屏障,神经内分泌和免疫系统,导致炎症反应.
- 肠道微生物群的改变与代谢综合征,心血管疾病和其他系统性病理有关.
研究的目的:
- 审查特定益生菌菌株的抗炎作用.
- 为了突出临床试验发现的益生菌对肠道疾病的疗效.
- 讨论影响益生菌有效性的因素,包括菌株,配方和治疗持续时间.
主要方法:
- 对治疗肠道疾病的益生菌补充剂临床试验的系统审查.
- 分析调查肠道微生物群对炎症状况的影响的研究.
- 对益生菌菌株特异性和治疗参数的证据的评估.
主要成果:
- 特定的益生菌菌株在临床试验中显示出显著的抗炎作用.
- 益生菌的有效性因菌株,配方,剂量和治疗时间而异.
- 长期服用益生菌通常是恢复肠道生态的必要条件.
结论:
- 益生菌补充剂可以有效地管理肠道疾病和相关炎症.
- 个性化益生菌方法考虑菌株特异性影响对于最佳结果至关重要.
- 需要进一步的研究来阐明机制,并优化各种炎症状况的益生菌疗法.
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