改变肠道微生物群组成与幼儿明确情绪调节的困难有关
Hideaki Fujihara1,2, Michiko Matsunaga1,2,3, Eriko Ueda1,2
1Graduate School of Education, Kyoto University, Yoshida-honmachi, Sakyo-ku, Kyoto 606-8501, Japan.
Microorganisms
|September 28, 2023
概括
学龄前儿童的肠道微生物群组成与情绪调节有关. 患有明确情绪调节 (EER) 风险的儿童表现出较高水平的与炎症相关的细菌,这表明肠道健康和早期情绪发育之间存在联系.
科学领域:
- 微生物组研究的研究.
- 发展心理学是发展心理学.
- 儿科卫生健康 儿科卫生健康
背景情况:
- 执行功能 (EF) 包括明确的情绪调节 (EER) 和认知控制 (CC).
- 童年EER影响成年人的精神和身体健康.
- 人们越来越认识到肠道微生物群 (GM) 对大脑功能及其作为健康生物标志物的作用和潜力.
研究的目的:
- 调查肠道微生物群组成与早期儿童执行功能 (EF) 风险之间的关联.
- 在3-4岁儿童中探索GM和明确情绪调节 (EER) 之间的关系.
主要方法:
- 招募了257名年龄在3-4岁的儿童.
- 通过使用"母亲报告的执行功能行为评级清单" (Mother-Reported Behavior Rating Inventory of Executive Function) 的学前版本评估EF.
- 通过16S rRNA基因测序分析了转基因成分 (α/β多样性,属丰富性).
主要成果:
- 患有EER风险的儿童表现出更高的细菌属*Actinomyces*和*Sutterella*.
- 研究结果表明,转基因与学龄前儿童的情绪处理密切相关.
- 患有EER风险的儿童表现出与炎症相关的细菌的更多存在.
结论:
- 幼儿时代肠道微生物群的组成与明确的情绪调节有关.
- 特定的细菌属可以作为EER风险的指标.
- 需要进一步的研究,以了解将转基因,炎症和EER发展联系在一起的机制.
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