发生了一种新的Salmonella Infantis变种,缺乏体质抗原
Alessandra Alessiani1,2, Gianfranco La Bella1, Adelia Donatiello1
1Istituto Zooprofilattico Sperimentare della Puglia e della Basilicata, Via Manfredonia 20, 71121 Foggia, Italy.
Microorganisms
|September 28, 2023
概括
在 brojlers中发现了缺乏关键抗原的耐多药沙门氏菌菌株. 这一发现对公共卫生具有重要意义,可能会影响沙门氏菌检测和控制战略.
科学领域:
- 兽医微生物学 兽医微生物学
- 食品安全 食品安全
- 基因组学就是基因组学.
背景情况:
- 沙门氏菌是 brojiler感染和人类沙门氏菌的常见原因.
- 沙门氏菌的一个特定变种,血清型 -:r:1,5,引起了公众健康的关注.
研究的目的:
- 从肉中分离出来的萨尔摩内拉婴儿菌株的表型,抗生素耐药性和基因组概况的特征.
- 调查新型沙门氏菌婴儿菌变种对公共卫生的影响.
主要方法:
- 从 brojler litter 和肉中分离出Salmonella Infantis菌株 (2018-2022 年).
- 表型分析,抗生素耐药性分析和全基因组测序.
- 特定基因 (blaCTX-M-1) 和等离子体不兼容性组 (IncFIB,IncX1) 的鉴定.
主要成果:
- 鉴定出了6种沙门氏菌幼虫菌株 (血清型 -:r:1,5,序列类型ST32).
- 所有的分离物体都表现出多重耐药性 (MDR).
- blaCTX-M-1基因存在于三种菌株中,其中一种菌株也携带IncX1.1.
结论:
- 这种变种沙门氏菌菌株的出现与了解不断变化的沙门氏菌种群有关.
- 缺少体质抗原对隔离和血清型定型提出了挑战,可能增加沙门氏菌感染传播的风险.
- 这突显了严重的公共卫生问题,需要进一步采取监测和控制措施.
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