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Updated: Jul 15, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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1,4-纳夫托金与蒂米丁衍生物的混合体:合成,抗癌活性和分子对接研究

Monika Kadela-Tomanek1, Kamil Krzykawski2, Adrianna Halama2

  • 1Department of Organic Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland.

Molecules (Basel, Switzerland)
|September 28, 2023
PubMed
概括

研究人员合成了新型的1,4-纳夫托基诺-胺杂交物来对抗癌症. 这些化合物表现出显著的抗癌活性,诱导头癌细胞系的亡,提供新的治疗途径.

关键词:
1,4-纳夫托基诺的使用方法在AZT,AZT是AZT.这是apoptotic的.头部和部癌症 头部和部癌症

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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