Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 15, 2025

Graphene Coatings for Biomedical Implants
13:21

Graphene Coatings for Biomedical Implants

Published on: March 1, 2013

21.3K

探索功能化石墨烯复合材料用于尿道导管应用.

Rita Teixeira-Santos1,2, Luciana C Gomes1,2, Rita Vieira1,2

  • 1LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.

Nanomaterials (Basel, Switzerland)
|September 28, 2023
PubMed
概括

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sedentary behaviour and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.

medRxiv : the preprint server for health sciences·2026
Same author

Sugar sweetened and artificially sweetened beverages, fruit and vegetable juices and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.

medRxiv : the preprint server for health sciences·2026
Same author

Correction: Exploring the impact of gender-related variables on health measures and perceived stress.

Frontiers in psychology·2026
Same author

Highly Efficient Bimetallic Catalysts Supported on Carbon Nanotubes for the NOx Reduction.

Nanomaterials (Basel, Switzerland)·2026
Same author

Surface Interactions between an Eco-Friendly Antifouling Agent and <i>Pseudoalteromonas tunicata</i> Membrane.

ACS applied bio materials·2026
Same author

Cyclam-based Cu(II) and Fe(III) complexes for antifouling coating development.

Dalton transactions (Cambridge, England : 2003)·2026

在PDMS涂层中的功能化石墨烯纳米板块 (N-GNP) 显著抑制了尿导管 (UC) 上的生物膜形成. 这种新型复合物减少了细菌细胞和培养能力,证明了改善UC涂层的潜力.

科学领域:

  • 生物材料科学 生物材料科学
  • 纳米技术纳米技术
  • 微生物学 微生物学

背景情况:

  • 石墨烯纳米板块 (GNP) 对生物医学应用具有宝贵的物理化学和抗微生物特性.
  • 尿导管 (UC) 生物膜带来了重大的临床挑战,需要先进的涂层材料.
  • 功能化石墨烯为开发有效的抗菌膜表面提供了一个有希望的途径.

研究的目的:

  • 为了研究功能化石墨烯纳米血板块 (N-GNP) 的抗菌膜疗效,将其纳入聚二甲基 (PDMS) 基质中,作为尿导管 (UC) 的涂层.
  • 评估N-GNP/PDMS复合物对单个和多个物种的细菌生物膜的影响,包括*金黄色葡萄球菌*,*假球菌*和*肺炎菌*.
  • 探索N-GNP的抗菌作用机制.

主要方法:

  • 合成和描述N-GNP/PDMS复合材料的方法.
  • 对复合材料的疏水性和表面粗性的评估.
  • 使用细胞计数和可培养性测定对单种和多种生物膜抗菌膜活性的评估.
  • 对生物膜结构的分析和对N-GNP的细菌细胞反应的探索.

主要成果:

  • 与纯PDMS相比,N-GNP/PDMS复合物表现出增强的疏水性和粗性.
  • 在单个物种生物膜中,观察到 *S. aureus* (64%), *P. aeruginosa* (41%) 和 *K. pneumoniae* (29%) 的细菌细胞数量显著减少.
关键词:
抗菌膜活动的抗菌膜活性.这是一个复合材料.多种多种生物膜.有的功能化石墨烯.尿导管是用于尿道的.

更多相关视频

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria
05:57

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Published on: October 4, 2024

883
Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.3K

相关实验视频

Last Updated: Jul 15, 2025

Graphene Coatings for Biomedical Implants
13:21

Graphene Coatings for Biomedical Implants

Published on: March 1, 2013

21.3K
Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria
05:57

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Published on: October 4, 2024

883
Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.3K
  • 在三种生物膜中,S. aureus生物膜培养能力下降了50%,总细胞减少了41%.
  • N-GNP诱导的膜透性变化和S. aureus中的反应性氧物种 (ROS),以及格拉姆阴性细菌中的细胞代谢变化.

    • 结论:

    • 该N-GNP/PDMS复合物有效地抑制尿导管上的生物膜的发展.
    • 功能化石墨烯纳米血板显示出针对常见尿病原体的显著抗菌膜特性.
    • N-GNP/PDMS复合涂料在提高性能和减少与尿导管相关的感染方面具有相当大的潜力.