患有代谢功能障碍相关脂肪肝疾病的患者的身体组成分析
Saori Onishi1, Akira Fukuda2, Masahiro Matsui1
1Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsukishi 569-8686, Japan.
Nutrients
|September 28, 2023
概括
评估了与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 的身体组成. 身体质量指数 (BMI) 和脂肪质量指数是MAFLD患者骨肌肉质量的关键指标.
科学领域:
- 代谢疾病 代谢疾病
- 身体组成分析 身体成分分析
- 肝脏健康 肝脏健康
背景情况:
- 与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 是一个日益严重的健康问题.
- 了解身体组成,特别是骨肌肉质量,对于管理MAFLD至关重要.
- 生物阻抗分析提供了一种方法来评估这个患者群体的身体组成.
研究的目的:
- 用MAFLD患者的生物阻抗分析来研究身体组成.
- 在MAFLD患者中确定与无脂肪质量指数 (FF指数) 相关的因素.
- 为了确定易于测量的标记物和MAFLD中的骨肌肉质量之间的关系.
主要方法:
- 生物阻抗分析用于测量2014年男性和949名患有MAFLD的女性的身体组成.
- 无脂肪质量指数 (FF指数) 被计算出来,骨肌肉质量下降被定义为FF指数<18kg/m2在男性中,<15kg/m2在女性中.
- 进行了单变量和多变量分析,以确定与FF指数相关的因素.
主要成果:
- FF指数与男性和女性的肌肉质量指数有很强的相关性 (r = 0.999).
- 根据年龄,BMI,脂肪肝严重程度和FIB4指数分层的骨肌肉质量下降的患病率.
- 在男性中,BMI,脂肪质量指数和腰围是与FF指数相关的重要因素. 在女性中,BMI和脂肪质量指数显著.
结论:
- 身体质量指数 (BMI) 是一种随时可用的标志物,可以作为MAFLD患者骨肌肉质量的有用指标.
- 由BMI反映的脂肪积累与MAFLD中的骨肌肉质量密切相关.
- 这些发现凸显了监测MAFLD管理中的身体组成的重要性.
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