坚持地中海饮食与多发性硬化症的严重程度有关
Monica Guglielmetti1,2, Wahidah H Al-Qahtani3, Cinzia Ferraris1,2
1Human Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.
Nutrients
|September 28, 2023
概括
坚持地中海饮食可能会改善多发性硬化症的结果. 较高的坚持与意大利患者患轻度至中度多发性硬化症 (MS) 的概率显著增加相关.
科学领域:
- 神经学 神经学
- 营养学 营养学 营养学
- 公共卫生 公共卫生
背景情况:
- 健康的生活方式,包括均衡饮食,可以改善多发性硬化症 (MS) 患者的临床参数和生活质量.
- 地中海饮食 (MedDiet) 是一种与各种健康益处相关的饮食模式.
- 研究MedDiet对MS严重程度的影响对于理解潜在的治疗策略至关重要.
研究的目的:
- 探索遵守地中海饮食和多发性硬化症 (MS) 在意大利患者队列中的严重程度之间的关联.
- 为了确定更高的MedDiet坚持是否与较轻微的MS症状或较慢的疾病进展相关.
主要方法:
- 评估了106名意大利MS患者 (pwMS) 的队列.
- 使用110项食物频率问卷收集饮食习惯.
- 使用Medi-Lite得分评估遵守MedDiet,并使用赫伯特尺度 (MSSS) 分级MS严重程度.
主要成果:
- 根据MedDiet的坚持,患者被分为三组:低,中,高.
- 对MedDiet的更高坚持与患有轻度至中度MS的概率增加了6.18倍 (95%CI:1.44,26.59).
- 没有MedDiet的单个成分,当单独分析时,显示与MS严重程度有显著的关联.
结论:
- 对地中海饮食的更高坚持可能与研究的意大利人群中多发性硬化症的较温和临床表现有关.
- 需要进一步的研究来阐明MedDiet成分可能影响MS发病和进展的具体机制.
- 未来的研究应该旨在复制这些发现,并研究MS管理中饮食干预的长期影响.
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