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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
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调节内皮功能的黄类药物的研究进展

Hao Li1, Qi Zhang1

  • 1The Basic Medical College, Shaanxi University of Chinese Medicine, Xianyang 712046, China.

Pharmaceuticals (Basel, Switzerland)
|September 28, 2023
PubMed
概括
此摘要是机器生成的。

自然的黄类化合物通过改善内皮功能来对抗心血管疾病. 它们提供抗炎和抗氧化剂的好处,显示出作为血管健康的补充剂和药物的潜力.

关键词:
没有,没有,没有,没有.生物可用性 生物可用性内皮质功能障碍 在内皮质功能障碍黄类化合物 黄类化合物氧化应激是一种氧化应激.

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科学领域:

  • 心血管科学 心血管科学
  • 药理学 药理学是指药理学的学科.
  • 营养科学 营养科学

背景情况:

  • 由氧化应激和炎症标志着内皮功能障碍,是心血管疾病 (CVD) 的核心.
  • 来自饮食和传统中医药的天然黄酸在调节内皮细胞方面表现有前途.
  • 黄素具有抗炎,抗氧化和抗衰老的特性,有利于血管健康.

研究的目的:

  • 探索饮食和传统中医药中黄类物质改善内皮功能障碍的机制.
  • 详细介绍这些黄素的新陈代谢和肠道微生物群相互作用.
  • 突出黄类药物作为治疗剂和食品补充剂在预防和治疗心血管疾病方面的潜力.

主要方法:

  • 在体外和体内对黄类药物对内皮细胞影响的研究的综述.
  • 分析参与由黄素调节内皮功能的信号通路.
  • 调查黄酸代谢,生物可用性和肠道微生物群的相互作用.
  • 对纳米粒子传递系统进行检查,以提高黄类药物的有效性.

主要成果:

  • 黄类药物调节关键信号通路,恢复内皮功能.
  • 黄类药物的有效性受到其代谢和与肠道微生物群的相互作用的影响.
  • 纳米颗粒配方可以显著提高黄类生物可用性和血管保护.

结论:

  • 饮食和传统中医药中的黄类化合物是内皮功能的强有力的调节剂.
  • 了解黄酸代谢和肠道相互作用对于治疗开发至关重要.
  • 黄类药物,特别是通过增强的输送系统,代表了预防和治疗心血管疾病的有希望的战略.