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基于伊米达索皮里丁的提亚衍生物作为潜在的抗糖尿病剂:合成,体外生物活性和分子建模方法

Rafaqat Hussain1, Wajid Rehman1, Shoaib Khan1

  • 1Department of Chemistry, Hazara University, Mansehra 21120, Pakistan.

Pharmaceuticals (Basel, Switzerland)
|September 28, 2023
PubMed
概括

合成了新的提亚衍生物,并测试了它们抑制α-葡萄糖酶的能力. 化合物4a和4o显示出最强的α-葡萄糖酶抑制,表明糖尿病管理的潜力.

关键词:
分子对接的分子对接.综合合成是一种合成.提亚醇的使用方法α-葡萄糖化酶的使用

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