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基托桑基纳米颗粒的进步用于肺部药物输送

Thiago Medeiros Zacaron1, Mariana Leite Simões E Silva2, Mirsiane Pascoal Costa1

  • 1Postgraduate Program in Pharmaceutical Science, Federal University of Juiz de Fora, Juiz de Fora 36036-900, Minas Gerais, Brazil.

Polymers
|September 28, 2023
PubMed
概括

奇托桑纳米颗粒为呼吸系统疾病提供了改善的肺部药物输送. 它们独特的特性提高药物的有效性,减少副作用,呈现出一个有前途的纳米医学方法.

关键词:
基多酸盐的使用方法基托桑衍生品 基托桑衍生品肺部输送 肺部输送 肺部输送肺部疾病 肺部疾病纳米颗粒是一种纳米粒子.药物输送到肺部的过程中.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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