抗生素耐药性ESKAPE病原体和COVID-19:超越流行病的流行病
Alessia Catalano1, Domenico Iacopetta2, Jessica Ceramella2
1Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via Orabona 4, 70126 Bari, Italy.
Viruses
|September 28, 2023
概括
由于滥用和获取不良,COVID-19大流行使抗生素耐药性恶化. 本综述考察了全球抗菌耐药性,重点关注关键病原体,如肠杆菌和青杆菌baumannii.
科学领域:
- 微生物学 微生物学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 抗生素耐药性是一个重大的全球健康威胁,由COVID-19大流行加剧.
- 诸如改变处方习惯,错误信息和治理问题等因素在疫情期间增加了对抗生素的滥用.
- 多抗药性 (MDR),广泛抗药性 (XDR) 和泛抗药性 (PDR) 细菌的兴起是一个关键的挑战.
研究的目的:
- 为全球抗菌药物耐药性状态提供最新的概述.
- 专注于关键的病原体,包括肠杆菌,阿辛托巴克特宝曼尼和Klebsiella pneumoniae.
- 分析这些关键细菌对常见抗生素的耐药性模式.
主要方法:
- 对当前全球抗菌耐药性数据的文献综述.
- 对特定高优先病原体的耐药性趋势的分析.
- 检查抗生素耐药性的机制和模式.
主要成果:
- 在全球范围内,由MDR,XDR,DTR,CR和PDR细菌引起的感染的流行率不断增加.
- 由于广泛的耐药性,治疗由肠杆菌,Acinetobacter baumannii和Klebsiella pneumoniae引起的感染存在重大挑战.
- 确定常见的抗生素类别,对这些病原体的疗效下降.
结论:
- COVID-19 流行病加剧了抗菌耐药性的危机,可能导致未来的耐药性流行病.
- 迫切需要全球战略来打击耐药细菌的传播,并保持抗生素的有效性.
- 对肠杆菌,A. baumannii和K. pneumoniae等关键病原体的持续监测和研究至关重要.
关键词:
在 COVID-19 疫情中,在DTR中,DTR是指DTR.一个逃跑者.在MDR中使用MDR.在PDR中使用PDR.这就是SARS-CoV-2病毒.这是XDRXDR.抗菌耐药性的抗菌药物.抗菌剂是一种抗菌剂.在后COVID时期.更多相关视频
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