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Updated: Jul 15, 2025

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
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抗病毒因子SERINC5损害了非自我DNA的表达

Yuhang Shi1, Sydney Simpson2, Shahad K Ahmed1

  • 1Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14620, USA.

Viruses
|September 28, 2023
PubMed
概括

限制因子SERINC5通过破坏病毒基因表达来阻碍人类免疫缺陷病毒 (HIV) 复制. 这影响了病毒的产生,揭示了除了阻止病毒进入之外的新宿主防御机制.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒在SERINC5中使用.异胎性DNA DNA 在子宫外.不属于自己的DNA.转录限制的转录限制

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