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Updated: Jul 12, 2026

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构建来自Aspergillus terreus的重组ZFP160作为丁脱氨酶酶

Sajitha Bijukumar1, Thandeeswaran Murugesan2, Anand Raj Dhanapal3

  • 1Cancer Therapeutics Laboratory, Department of Microbial Biotechnology, Bharathiar University, Coimbatore, Tamil Nadu, India.

Biotechnology and applied biochemistry
|September 28, 2023
PubMed
概括

这项研究详细介绍了来自Aspergillus terreus的pterin deaminase的分子功能和酶机制,揭示了其潜在的抗癌特性. 研究探讨了治疗应用的蛋白质表达,净化和基质相互作用.

关键词:
这是一种Aspergillus terreus.分子克隆分子克隆氨基基酸酶的氨基基酸酶.素脱氨酶的作用是什么在ZFP160中,ZFP160.

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Allosteric Proteins-ATCase01:19

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Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis pathway,...