期刊俱乐部:抗CD19化学抗原受体T细胞疗法用于耐火性系统性红斑狼
Afroditi Boulougoura1, Hannah Gendelman1, Natalya Surmachevska1
1Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
ACR open rheumatology
|September 28, 2023
概括
针对CD19的化学抗原受体 (CAR) T细胞疗法在5名耐治疗系统性红斑狼 (SLE) 患者中显示出有前途的结果. 所有患者都实现了缓解,持续无药缓解和良好的耐受性.
科学领域:
- 免疫治疗是一种免疫疗法.
- 血液学 血液学 血液学
- 类风湿病学 类风湿病学
背景情况:
- 系统性红斑狼 (SLE) 仍然是对现有免疫抑制疗法耐药的患者的挑战.
- CD19仿真抗原受体 (CAR) T细胞疗法为自身免疫性疾病中B细胞枯竭提供了一种新的方法.
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