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在磁共振环境中进行定量传感测试:考虑热敏度和患者安全
Ayeong Jenny Kim1,2, Edina Szabo1,2, Claire E Lunde1,2,3
1Department of Anesthesiology, Critical Care, and Pain Medicine, Pain and Affective Neuroscience Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Frontiers in pain research (Lausanne, Switzerland)
|September 28, 2023
概括
磁共振成像 (MRI) 环境改变了热疼痛的敏感性. 这项研究发现MRI内疼痛值显著增加1.1°C,影响健康人群和慢性疼痛患者.
科学领域:
- 神经科学是一个神经科学.
- 医疗成像医学成像
- 疼痛研究 疼痛研究
背景情况:
- 量化感官测试 (QST) 对于理解疼痛感知至关重要.
- 将QST适应磁共振 (MR) 环境是神经通路的机械洞察所必需的.
- MR环境对热感知的影响仍然未被评估.
研究的目的:
- 为了评估温度灵敏度在MR环境的外部和内部的差异.
- 测试MR环境影响报告的疼痛敏感性的假设.
主要方法:
- 健康的参与者和慢性疼痛队伍在MRI扫描仪之外接受了热QST.
- 参与者评价热刺激,疼痛达到7/10强度 (利克尔特尺度0-10).
- 该程序在3.0TMRI扫描仪内重复.
主要成果:
- 在环境之间观察到疼痛值的统计学上显著的1.1°C增加.
- 热敏度的这种变化在健康和慢性疼痛参与者中是一致的.
结论:
- MR 环境显著改变了热性疼痛感知.
- 这些发现为MR安全提供了信息,增强了对疼痛路径的理解,并突出了MR环境对感知影响研究的影响.
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