在瑞典人口中扩大上升大动脉的患病率和决定因素:一个病例控制研究
Eva Swahn1,2, Hanna Lekedal1,2, Jan Engvall2,3,4
1Department of Cardiology, Linköping University Hospital, Linköping, Sweden.
European heart journal open
|September 28, 2023
概括
上升性大动脉扩张影响1.4%的中年人群,特别是男性. 这种情况与大动脉问题和高血压有关,而不是亚临床动脉样硬化.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 血管医学 血管医学
背景情况:
- 上升性大动脉 (AA) 扩张可以无症状,直到发生剖析或破裂等关键事件.
- 增加胸部成像的使用有助于早期检测,但患病率和决定因素需要澄清.
研究的目的:
- 在瑞典中年人群中,识别和描述上升性大动脉扩张的个体.
主要方法:
- 使用了瑞典心肺生物图像研究 (SCAPIS) 的5058名参与者 (50-65岁).
- 通过CT血管造影确定了AA直径≥40mm的病例;对照组AA直径<40mm.
- 使用心声回声,血压,脉冲波速度,冠状动脉化和带超声波来表征受试者.
主要成果:
- 确定了70例病例 (平均AA直径为44毫米,男性为77%) 和146例对照 (平均AA直径为34毫米).
- 双主动脉和主动脉功能障碍在病例中更为普遍.
- 病例呈现出明显更高的办公室和家庭血压,以及更高的脉冲波速度.
结论:
- 在这个队列中,上升性大动脉扩张的患病率为1.4%.
- 发现与男性性别,大动脉病理和透气血压的积极关联.
- 在AA扩张和亚临床动脉样硬化之间没有观察到任何关联.
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