在患有血栓细胞减小症的患者中,出现神经切术后出血的风险
Jad P AbiMansour1, Vishal Garimella1, Bret T Petersen1
1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Therapeutic advances in gastrointestinal endoscopy
|September 28, 2023
概括
在血小板数量较低 (血小板缺血) 的患者体内缩切除术 (ES) 显示出与一般人群相似的出血率. 患有恶性瘤的患者在ES后面临更高的出血风险.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 在内镜切除术 (ES) 后,不良事件 (AEs) 可能发生在高达10%的患者中.
- 胃肠道出血是内镜逆行胆血管细胞谱 (ERCP) 程序后的一个重要问题.
研究的目的:
- 为了确定患有ES的血小板缺血患者出血的发生率.
- 为了确定与该患者群体中ES后出血相关的风险因素.
主要方法:
- 进行了一项回顾性观察性队列研究.
- 分析了2017年5月至2020年12月期间接受ES的血小板减少 (血小板 <150,000/μL) 患者.
- 通过手动图表审查确定出血事件 (即时和延迟).
主要成果:
- 在221名患有血小板缺血的患者中,5%的患者立即出血,0.9%的患者有延迟出血.
- 恶性病与明显增加的出血风险有关 (36.4%对11.4%,p=0.037).
- 血小板数本身与出血风险没有相关性.
结论:
- 经受ES治疗的血小板缺血患者的出血率与ES的一般AE率相似.
- 患有活跃恶性瘤的患者和经历立即出血的患者需要密切监测潜在的出血并发症.
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