相关实验视频
Updated: Jul 15, 2025
11:29
miRNA Expression Analyses in Prostate Cancer Clinical Tissues
Published on: September 8, 2015
10.9K
巴基斯坦前列腺癌的流行:系统性审查和元分析
Sohail Akhtar1, Fazal Hassan1, Sadique Ahmad2
1Department of Mathematics and Statistics, The University of Haripur, Haripur, Pakistan.
Heliyon
|September 28, 2023
概括
这一元分析发现,巴基斯坦的前列腺癌综合患病率为5.20%,区域差异很大,随着时间的推移趋势越来越大. 进一步的研究和干预是至关重要的.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 前列腺癌是全球主要的健康问题,尤其是男性.
- 它在巴基斯坦的流行率在研究中显示出相当大的差异.
- 这项研究解决了对巴基斯坦前列腺癌发病率的综合了解的需求.
研究的目的:
- 为了确定巴基斯坦前列腺癌的综合患病率.
- 为了确定前列腺癌的相关风险因素.
- 为巴基斯坦前列腺癌当前的流行病学景观提供全面的概述.
主要方法:
- 对多个数据库 (PubMed,科学网,谷歌学者,本地数据库) 进行了系统的搜索.
- 用随机效应的元分析来计算聚合的流行率和相对风险.
- 数据提取,偏差风险评估和元回归由两名独立调查人员进行.
主要成果:
- 分析包括11项研究,涉及184,384名参与者,显示前列腺癌总体综合患病率为5.20%.
- 观察到实质性的异质性 (I2 = 98.5%),在Khyber Pakhtunkhwa (8.29%) 和Punjab (8.09%) 的流行率最高,在Sindh (3.30%) 的流行率最低.
- 前列腺癌患病率显著增加,从3.88% (2000-2010年) 增加到5.80% (2011-2023年).
结论:
- 这一元分析提供了对巴基斯坦前列腺癌患病率的关键见解.
- 这些发现强调了有针对性的公共卫生战略和持续研究的必要性.
- 解决前列腺癌需要在监测和干预方面持续努力.
相关概念视频
01:20Disorders of the Male Reproductive System
447
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
447
01:21Cancer Survival Analysis
380
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
380
01:08Prevalence and Incidence
619
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
619
01:33Proteomics
7.4K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.4K