产前和产后暴露于BPA及其类似物 (BPS,BPF) 和过敏疾病之间的关系
Monika Weteska1, Aleksandra Zwolińska1, Kornelia Pisarska-Troczyńska1
1Medical University of Lodz, Łódź, Poland (Department of Pediatrics and Allergy, Copernicus Memorial Hospital).
International journal of occupational medicine and environmental health
|September 28, 2023
概括
怀孕和童年期间接触双A (BPA) 与儿童过敏有关. 需要对双S (BPS) 和双F (BPF) 的影响进行更多的研究.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 儿科过敏 儿科过敏
背景情况:
- 双是日常生活中普遍存在的内分泌干扰化学物质.
- 在关键发育阶段 (产前,婴儿,幼儿) 暴露会导致不良健康结果,包括呼吸道和免疫系统问题.
- 过敏疾病在儿童群体中越来越令人担忧.
研究的目的:
- 对产前和产后接触双A (BPA),双S (BPS) 和双F (BPF) 对儿童过敏疾病发展的影响进行审查.
- 综合最近流行病学研究的发现.
- 识别知识缺口和未来研究领域.
主要方法:
- 在PubMed,Scopus和Web of Science数据库中的系统文献搜索.
- 纳入标准:2015年以来发表的研究,英语,同行评审期刊.
- 对2648项已识别的研究进行了资格选,结果包括了8项流行病学研究.
主要成果:
- 有证据表明,孕妇在怀孕或童年期间暴露于BPA和儿童发展过敏疾病之间存在关联.
- 大多数审查的研究报告说,BPA暴露与至少一种类型的过敏状况之间存在正相关性.
- 数据不足和不一致的发现阻止了关于BPS和BPF暴露的影响的最终结论.
结论:
- 母亲暴露于BPA可能会增加儿童过敏疾病的风险.
- 进一步的研究是必不可少的,以阐明具体机制,并确定有关BPS和BPF暴露的脆弱人群.
- 需要进行长度研究来确认关联,并了解双暴露对健康的长期影响.
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