通过深思熟虑的抗微生物敏感性测试和报告策略指导抗微生物药物管理:在2023年更新的方法
Virginia M Pierce1, Tanaya Bhowmick2, Patricia J Simner3,4
1Department of Pathology, University of Michigan Medical School , Ann Arbor, Michigan, USA.
Journal of clinical microbiology
|September 28, 2023
概括
更新的临床和实验室标准研究所 (CLSI) M100指南提供了现代化的抗菌素敏感性测试和报告策略. 这些修订支持抗菌药物管理计划,使机构能够创建个性化测试和报告算法.
科学领域:
- 临床微生物学 临床微生物学
- 抗微生物药物管理委员会
- 传染性疾病 传染性疾病
背景情况:
- 对抗微生物药物敏感性测试和报告准则对于抗微生物药物管理计划至关重要.
- 临床和实验室标准研究所 (CLSI) M100文件的表1历来指导了敏感性测试和报告算法.
- 目前的临床实践需要更新,因为新的抗微生物药物,耐药机制,多药耐药生物和治疗建议.
研究的目的:
- 为了引入更新的CLSI M100-Ed33表 1.
- 描述在2023年版中对表1进行的修订.
- 证明这些修订表的应用在创建机构抗微生物敏感性测试和报告策略时.
主要方法:
- 一个特设工作组对CLSI M100表1进行了修订.
- 纳入当前的临床实践,新药,耐药性模式和治疗指南.
- 基于选择性和级联报告概念的战略开发.
主要成果:
- 在CLSI M100-Ed33表1中更新的内容反映了当前的抗微生物环境.
- 修订后的表格支持创建个性化的测试和报告策略.
- 临床图片说明了更新指南的实际应用.
结论:
- 更新的CLSI M100-Ed33表1为机构提供了一个框架,以加强其抗菌药物管理倡议.
- 使用这些指南,可以有效地开发个性化测试和报告策略,利用选择性和级联报告.
- 这些修订旨在优化抗微生物药物的使用,并打击抗微生物药物耐药性.
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