针对尼日利亚重症患者的抗生素指南
R O Oladele1,2, A O Ettu3, N Medugu4
1College of Medicine, University of Lagos, Lagos State, Nigeria.
West African journal of medicine
|September 28, 2023
概括
针对重症监护病房 (ICU) 的新尼日利亚抗菌指南打击抗菌耐药性. 这些以证据为基础的建议改善了重症监护机构的患者结果和抗生素管理.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 抗微生物药物管理委员会
背景情况:
- 不适当使用抗微生物药物导致全球抗微生物药物耐药性.
- 抗生素管理计划可以减少耐药性,改善患者的治疗结果,并提供经济效益.
- 尼日利亚缺乏针对重症病患在重症监护室 (ICU) 的特定抗菌指南.
研究的目的:
- 为尼日利亚重症监护室的重症患者制定基于证据的抗微生物治疗指南.
- 为了解决当地缺乏指导方针来管理这种脆弱人群中的感染.
- 促进有效的抗生素管理和打击尼日利亚ICU中的抗菌素耐药性.
主要方法:
- 一个由12名专家组成的多学科委员会制定了指导方针.
- 建议是基于已公布的数据和来自尼日利亚三个重症监护室的当地前性抗生素图.
- 在委员会成员之间通过共识批准了指导方针,考虑到药物的可用性.
主要成果:
- 最常见的病原体是Candida albicans和Pseudomonas aeruginosa,它们是最常见的病原体.
- 针对包括肺炎,皮肤和软组织感染,血液感染和尿路感染在内的各种感染,制定了具体的经验性抗生素建议.
- 艾米卡辛,胆固醇,聚米辛B,美罗,阿莫西西林-克拉夫兰酸盐,,皮佩拉西林-塔扎巴克坦,可纳和万科米辛是基于疗效和局部耐药性模式推的药物之一.
结论:
- 制定了针对尼日利亚的,基于证据的,针对重症病房重症患者的抗菌指南.
- 实施将支持学习,加强管理活动,并为未来的指导方针更新提供基础.
- 这些指导方针旨在优化抗微生物药物的使用,并改善尼日利亚ICU的患者护理.
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