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在患有内脏莱什曼病症的患者中推迟诊断

Andrea Poloni^1,2, Andrea Giacomelli³, Mario Corbellino¹

¹III Infectious Diseases Unit, III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Via G.B. Grassi 74, 20157, Milan, Italy.

Internal and emergency medicine

|September 28, 2023

概括

诊断内脏莱什曼病 (VL) 需要时间,特别是对于免疫功能低下的患者. 与其他群体相比,艾滋病毒感染者 (PLWH) 经历了较短的VL诊断延迟.

科学领域:

传染性疾病传染性疾病
临床医学临床医学
寄生虫学的寄生虫学

背景情况:

内脏莱什曼病 (VL) 是一种严重的寄生虫病,需要及时诊断.
在VL的诊断延迟可能导致长期的疾病和增加的发病率.
了解影响诊断延迟的因素对于改善患者治疗结果至关重要.

研究的目的:

为了估计内脏莱什曼病 (VL) 的诊断延迟时间.
为了确定潜在的更长的诊断延迟的患者群体.
分析免疫状态对VL诊断时间的影响.

主要方法:

进行了一项回顾性观察性研究.
分析了2005年1月至2022年3月期间确诊的VL确诊病例的数据.
诊断延迟计算为从第一次医疗保健接触到实验室诊断的时间.

主要成果:

对VL的中位数诊断延迟时间为54天.
艾滋病毒感染者 (PLWH) 的中位延迟时间最短 (31天).
接受免疫抑制治疗的患者经历了最长的中位延迟时间 (329天).
50%的患者在VL诊断之前至少有一次先前的医疗遭遇.
由于诊断延迟,六名患者接受了不正确的治疗.

结论:

内脏莱什曼病的诊断延迟是显著的,特别是在接受免疫抑制治疗的患者中.
在像PLWH这样的特定人群中,可以实现及时诊断.
改善VL的诊断途径至关重要,以减少患者的痛苦和不适当的治疗.

关键词:

意识意识意识意识艾滋病病毒艾滋病病毒艾滋病病毒免疫抑制是一种免疫抑制.错过的机会错过的机会腹部莱什曼病是一种内脏的莱什曼病.

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