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Updated: Jul 15, 2025

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BML-281通过调节Wnt/Ca2+和Wnt/PCP信号通路来促进神经元的分化

Jiyun Choi1, Seoyeon Gang1,2, Mahesh Ramalingam1

  • 1Department of Physiology, Chonnam National University Medical School, Jellanamdo, 58128, Republic of Korea.

Molecular and cellular biochemistry
|September 28, 2023
PubMed
概括

BML-281是一种基因素脱乙酶6 (HDAC6) 抑制剂,促进神经母细胞细胞分化成成熟的神经元. 这通过Wnt信号通路的激活发生,这表明神经元细胞死亡的潜在治疗应用.

关键词:
在BML-281中使用.这是一种HDAC抑制剂.神经元分化的不同.非正规的 wnt 信号通路没有信号通路.

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