温度-中性粒细胞-多器官衰竭分级作为Fournier炎的预后指标
Deniz Tazeoglu1, Sami Benli1, Tahsin Colak1
1Department of General Surgery, Faculty of Medicine, Mersin University, Mersin, Turkey.
Surgical infections
|September 28, 2023
概括
新的温度-中性粒细胞-多器官衰竭 (TNM) 评分系统有效预测Fournier炎患者的死亡率. 较高的TNM分数与死亡风险增加相关,有助于个性化治疗策略.
科学领域:
- 医学科学 医学科学 医学科学
- 手术瘤学手术瘤学
- 传染性疾病 传染性疾病
背景情况:
- 严重性评分系统对于个性化的患者管理和风险评估至关重要.
- 四叶角 (FG) 是一种严重的死性感染,需要准确的预后评估.
研究的目的:
- 评估温度-中性粒细胞-多器官衰竭 (TNM) 评分系统在Fournier瘤患者的预后重要性.
- 评估TNM系统在预测FG患者死亡率方面的实用性.
主要方法:
- 一个单中心,横截面,回顾性研究分析了167名FG患者在2012年至2022年间进行手术.
- 收集的数据包括人口统计,手术前发现,体温,中性粒细胞比率,多器官衰竭存在,TNM得分和生存率.
- 患者被分为两组:术后医院死亡率和生存率.
主要成果:
- 与得分为1-2 (p < 0.001) 的患者相比,TNM得分为3-4阶段的患者的死亡频率明显更高 (p < 0.001).
- 死亡风险在65岁以上的患者 (4.80倍) 和伴随性疾病患者 (4.56倍) 中显著增加.
- 与得分为1-2的患者相比,TNM得分为3-4的患者死亡风险增加了9.38倍.
结论:
- 使用简单的临床和实验室数据的TNM评分系统是预测Fournier瘤死亡率的快速和有效工具.
- TNM系统的临床应用可以有利于FG和其他深层软组织感染的管理.
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