社区社会经济劣势和出生体重异常
Kartik K Venkatesh1, Lynn M Yee, Jasmine Johnson
1Departments of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio, Northwestern University, Chicago, Illinois, Indiana University, Indianapolis, Indiana, Case Western Reserve University, Cleveland, Ohio, University of Pittsburgh, Pittsburgh, Pennsylvania, Columbia University, New York, New York, University of Utah, Salt Lake City, Utah, University of Pennsylvania, Philadelphia, Pennsylvania, University of Texas Medical Branch, Galveston, Texas, and University of California, Irvine, School of Medicine, Orange, California; and RTI International, Durham, North Carolina.
社区社会经济劣势与新生儿出生体重异常有关. 贫困地区的孕妇有更高的几率分娩的婴儿是怀孕年龄较小或怀孕年龄较大的婴儿.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生殖健康 生殖健康
背景情况:
- 社会经济因素显著影响怀孕的结果.
- 区域贫困指数 (ADI) 量化了社区层面的社会经济劣势.
- 了解社区劣势对出生体重的影响对于有针对性的干预至关重要.
研究的目的:
- 调查邻里社会经济劣势,以ADI衡量,与异常出生体重的风险之间的联系.
- 确定较高的面积剥夺水平是否与分娩新生儿的可能性增加相关,这些新生儿对于妊娠年龄来说很小 (SGA) 或对于妊娠年龄来说很大 (LGA).
主要方法:
- 对前性NuMoM2b队列研究的二次分析.
- 参与者的地址被地理编码,并与2015年区域贫困指数 (ADI) 联系起来.
- 调整为混因子的多项逻辑回归模型分析了ADI四分位数与SGA/LGA结果之间的关联.
主要成果:
- 较高的ADI四分位数与分娩SGA新生儿的概率增加有关 (最高四分位数中的aOR为1.32).
- 在较高的ADI四分位数 (aORs从1.40到1.47) 中观察到LGA新生儿分娩的几率增加.
- 这些关联在对潜在的混变量进行调整后仍然存在.
结论:
- 出生于居住在社会经济弱势社区的无双双人父母的新生儿面临着异常出生体重的更高风险.
- 地区贫困是与SGA和LGA结果相关的重要因素.
- 调查结果强调需要制定公共卫生战略,解决母婴健康方面的社会经济差异.
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