被诊断为乳腺瘤的妇女的净存活率:瑞士的一项基于人口的研究
Nena Karavasiloglou1,2,3, Eleftheria Michalopoulou1,2, Manuela Limam2
1Division of Chronic Disease Epidemiology, Institute for Epidemiology, Biostatistics and Prevention, University of Zurich, Zurich, Switzerland.
Swiss medical weekly
|September 28, 2023
概括
乳腺癌 in situ (一种非侵袭性乳腺癌形式) 通常先于侵袭性瘤,这些瘤更早被检测出来. 现场乳腺癌患者的5年净生存率非常好.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 乳腺癌 in situ (BCIS) 的发病率增加.
- 关于BCIS患者预后的有限数据.
- 需要比较具有和没有先前的BCIS的侵入性瘤.
研究的目的:
- 根据之前的BCIS诊断,比较侵袭性乳腺瘤的特征.
- 估计不同类型乳腺瘤的5年净存活率.
- 研究BCIS对侵袭性乳腺癌预后的影响.
主要方法:
- 分析了2003-2016年间被诊断患有乳腺瘤的女性的数据.
- 使用审查权重的逆概率进行净生存分析 (Pohar Perme估计器).
- 瘤特征和生存率的比较.
主要成果:
- 在BCIS后的侵袭性瘤更早被检测出来,缺少的数据也更少.
- 对于BCIS的5年净存活率:1.02 (95% CI:1.01-1.03).
- 没有先前的BCIS侵袭性乳腺癌的5年净生存率:0.89 (95%CI:0.88-0.90).
- 在BCIS后侵袭性乳腺癌的5年净存活率:0.92 (95% CI:0.85-1.01).
结论:
- 在BCIS之前的侵入性乳腺瘤更频繁地在早期阶段被检测出来.
- 总体而言,乳腺瘤患者的5年净生存率很好.
- BCIS可能与随后侵袭性乳腺癌的更好的检测和预后有关.
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