IPO7通过p38 MAPK和NF-κB信号通路促进人类牙纸细胞中脂聚糖诱导的炎症反应

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Ziqiu Xiao1, Yue Zhang1, Yawei She1

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University.

Molecular immunology
|September 28, 2023
PubMed
概括

进口蛋白7 (IPO7) 在牙髓炎,牙髓炎的炎症中升高. 减少IPO7通过抑制p38 MAPK和NF-κB通路来抑制炎症性细胞因子,为脉炎提供了潜在的治疗标.

关键词:
人类牙纤维细胞 (hDPCs)首次公开募股7 IPO7炎症 炎症是一种炎症.脂聚糖化物 (LPS) 是一种在 NF-κBB 中.在P38 MAPKK中使用.这就是Sirt2的原因.

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