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Updated: Jul 15, 2025

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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瑞因与铜离子的氧化还原相互作用而通过反应性氧物种的产生引起特定地点的DNA损伤

Yuichiro Hirao1, Hatasu Kobayashi2, Yurie Mori2

  • 1Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie, Japan; Department of Home Care Nursing, Mie Prefectural College of Nursing, Tsu, Mie, Japan.

Mutation research. Genetic toxicology and environmental mutagenesis
|September 28, 2023
PubMed
概括

与铜 (Cu) 结合的米瑞 (MYR) 通过氧化应激引起DNA损伤. 这种机制涉及过氧化和铜离子,导致DNA链断裂和基变化.

关键词:
8-oxo-7,8-dihydro-2′-deoxyguanosine的使用情况.变异性突变物 变异性突变物药理学活动 药理学活动类化合物 类化合物亲氧化剂是一种亲氧化剂.

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