认知储备对慢波睡眠与社区老年人认知之间的关联的影响
Valentin Ourry1,2, Stéphane Rehel1,2, Claire André1,2
1Normandie University, UNICAEN, INSERM, U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Institut Blood and Brain @ Caen-Normandie, Cyceron, France.
认知储备 (CR) 可以保护老年人免受影响记忆力的睡眠障碍. 较高的CR水平有助于维持认知功能,即使减缓了慢波睡眠 (SWS).
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 睡眠医学 睡眠医学
背景情况:
- 慢波睡眠 (SWS) 对认知至关重要,但随着年龄的增长而下降.
- 老年人睡眠质量和认知功能之间的关系是可变的.
- 认知储备 (CR) 可能会影响睡眠如何影响认知.
研究的目的:
- 调查CR是否调节SWS对老年人认知功能的影响.
- 为了确定更容易受到睡眠障碍认知后果影响的个体.
- 探索终身认知参与对与年龄相关的睡眠变化的保护作用.
主要方法:
- 在135名认知完整的老年人中进行了多睡眠和神经心理评估.
- 用了两种终身认知参与的测量方法作为CR的代理.
- 线性回归和相互作用分析检查了SWS,CR和认知得分 (执行功能,情节性记忆).
主要成果:
- SWS与情节性记忆有积极的关联,但与执行功能无关.
- CR代理显著调节了SWS和认知表现之间的关联.
- 具有较高CR的个体保持了认知功能,尽管SWS水平较低.
结论:
- 认知储备可以缓冲与年龄相关的SWS下降的负面认知影响.
- 这项研究提供了CR保护认知从睡眠变化在衰老的第一个证据.
- 了解CR的作用可以帮助识别患有睡眠障碍风险的老年人.
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