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Updated: Jul 15, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
儿童原发性骨淋巴瘤的MR特征
Patrick Duffy1, Kirsten Ecklund2
1Boston Children's Hospital, Department of Radiology, Harvard Medical School, Boston, MA, USA. Patrick.duffy@childrens.harvard.edu.
骨的小儿原发性淋巴瘤往往呈现为多焦点性疾病,经常涉及膝关节附近的囊. 磁共振成像 (MRI) 发现,如心脏病似增强和软组织胀,表明这种罕见的癌症.
科学领域:
- 儿科放射学 儿科放射学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 骨头的原发性淋巴瘤是儿童罕见的一种非霍奇金淋巴瘤.
- 在儿科病例中,典型的磁共振成像 (MRI) 功能没有得到充分的记录.
研究的目的:
- 确定诊断时儿童中原发性骨淋巴瘤的特征性MRI发现.
- 描述治疗后的儿童原发性骨淋巴瘤的MRI表现.
主要方法:
- 对10名患有活检证明的原发性骨淋巴瘤的儿科患者的MRI,X光学和PET成像的回顾性审查.
- 分析损伤位置,T1/T2信号,增强模式,皮质完整性,软组织参与和淋巴腺病变.
- 与治疗计划和随访结果的相关性.
主要成果:
- 多焦点性疾病发生在40%的患者中,大腿部和膝盖区域的形病变很常见 (分别为70%和80%).
- 常见的MRI发现包括类似心脏病发作的T2外观 (70%) 和增强 (88%),利的T1边缘 (60%),软组织胀 (80%),偶尔出现皮质干扰 (30%).
- 所有患者在随访MRI上显示残留的骨异常,经常保持类似心脏病发作的外观.
结论:
- 儿科原发性骨淋巴瘤的MRI关键指标包括多焦点性,体参与 (特别是在膝盖周围),类似心脏病发作的增强,尖的T1边缘和相邻的软组织胀.
- 在治疗后的MRI中预计会出现残留的骨异常.
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