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针对GPR132治疗糖尿病的化合物的功能查和合理设计

Jia-Le Wang1, Xiao-Dong Dou2, Jie Cheng3,4

  • 1State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China.

Nature metabolism
|September 28, 2023
PubMed
概括

研究人员确定了一种G蛋白结合受体132 (GPR132) 信号通路,涉及导致2型糖尿病的脂质介质. 用一种新的抗剂向这种途径,可以逆转小鼠的代谢功能障碍,从而提供一种新的治疗策略.

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