相关实验视频
Updated: Jul 15, 2025

08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
7.2K
导致北印度性结肠炎爆发的因素-一个病例控制研究
Vishavdeep Singh Rana1, Gaurav Mahajan2, Amol N Patil3
1Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
BMC gastroenterology
|September 28, 2023
概括
对性结肠炎疗法的不良遵守以及最近使用抗生素或替代医学与印度的疾病爆发有关. 改善患者对药物坚持的教育对于管理性结肠炎 (UC) 爆发至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠道疾病研究研究
- 临床流行病学临床流行病学
背景情况:
- 性结肠炎 (UC) 是一种慢性疾病,具有缓解期和复发期 (爆发) 的特征.
- 在印度人口中,UC爆发的触发因素并未得到充分理解.
- 识别爆发预测因素对于有效的疾病管理至关重要.
研究的目的:
- 调查与北印度性结肠炎爆发相关的因素.
- 将经历爆发的患者与缓解期的患者进行比较.
- 确定干预的潜在目标,以减少爆发频率.
主要方法:
- 研究人员对84名UC患者进行了前性病例控制研究 (51例发作,33例缓解).
- 爆发被SCCAI评分 (≥5) 和内活动定义;缓解由SCCAI (<4) 和正常便calprotectin.
- 通过问卷收集了最近感染,压力,药物使用 (抗生素,止痛药),治疗坚持以及补充和替代疗法 (CAM) 使用的数据.
主要成果:
- 虽然感染,压力和饮食因素相似,但UC发作患者的抗生素使用率较高 (29.4%vs6.1%),治疗坚持不良 (50.9%vs15.2%),以及CAM摄入量 (70.6%vs33.3%).
- 缺乏坚持被归因于成本,感知治愈,和害怕副作用.
- 在爆发组中,提奥普林的使用率较低 (15.7%与36.4%相比).
结论:
- 不坚持治疗和最近使用CAM和抗生素与印度的UC爆发有关.
- 建议采取教育干预措施,促进对IBD治疗方法的知识和遵守.
- 进一步研究印度背景下特定的爆发触发器是有必要的.
关键词:
坚持的坚持 坚持的坚持抗生素 抗生素是一种抗生素.费用 费用 费用 费用 费用 费用 费用克罗恩氏病是什么 克罗恩氏病是什么炎症性肠病是一种炎症性肠病.无抗炎药 (NSAIDs) 是一种无抗炎药.压力 压力 压力 压力性结肠炎是一种更多相关视频
相关概念视频
Inflammatory Bowel Disease I: Ulcerative Colitis
207
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
207
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
348
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
348
Inflammatory Bowel Disease II: Crohn's Disease
279
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
279
Chronic Bowel Disorders: Introduction
474
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
474
Drugs for Treatment of Ulcerative Colitis in IBD
164
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
164
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
620
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
620

