低压肺膜对腹腔镜胆囊切除术疼痛和炎症的影响:一项随机对照临床试验
Mohammad Rashdan1, Salam Daradkeh2, Mutasim Al-Ghazawi3
1Department of General Surgery/ Minimally invasive surgery, School of Medicine, Jordan University Hospital, The University of Jordan, Amman, Jordan. Rashdan4salt@yahoo.com.
BMC research notes
|September 28, 2023
概括
在腹腔镜胆囊切除术期间的低压肺上皮膜可以减少术后疼痛和炎症标志物. 这种技术是安全有效的,可与标准压力方法相比较.
科学领域:
- 最少侵入性的手术
- 外科手术炎症 在外科手术炎症.
- 疼痛管理 疼痛管理
背景情况:
- 在腹腔镜胆囊切除术中,标准的肺膜压力是12-14mmHg.
- 降低腹腔内压力可以减少术后疼痛,改善血液动力学稳定性.
- 关于低压肺上皮膜对炎症标志物的影响的研究有限.
研究的目的:
- 为了评估低压肺上皮层 (8-10 mmHg) 与标准压力 (12-14 mmHg) 对术后疼痛的影响.
- 评估低压肺上皮膜对十个关键炎症标志物的影响.
- 为了比较操作结果和低压和标准压的肺膜之间的可行性.
主要方法:
- 预期的,双盲,随机对照试验.
- 100名接受选择性腹腔镜胆囊切除术的患者被随机 (1:1) 分给低压或标准压力组.
- 收集和分析了术后变量,包括疼痛评分和炎症标志物.
主要成果:
- 低压组的患者在术后6小时报告了明显较低的中位数疼痛评分 (5对6,p=0.021).
- 10个炎症标志物中的8个显示出低血压组中较低水平的趋势,尽管在统计学上并不显著.
- 无论外科医生的经验如何,手术时间和手术困难在各组之间都是可比的.
结论:
- 腹腔镜胆囊切除术中的低压肺关节与手术后疼痛减少和较低的炎症反应有关.
- 这种技术是可行的,并显示出与标准压力肺上皮管相比的并发症率.
- 这种方法提供了潜在的改善患者康复概况.
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