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相关概念视频

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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Connective Tissue Cell Types01:22

Connective Tissue Cell Types

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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
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Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

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Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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相关实验视频

Updated: Jul 15, 2025

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
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减肥手术后维生素D度的变化

Vanessa Mayana Alves Baad1, Narriane Chaves Pereira de Holanda1,2, Juliana Fonseca Nogueira Alves3

  • 1Faculty of Medical Sciences, University of Pernambuco, Recife, Pernambuco, Brazil.

Journal of obesity
|September 29, 2023
PubMed
概括

减肥手术会影响维生素D水平和身体成分. 路克斯-en-Y胃绕道和垂直袖胃切除术都有效地减少脂肪质量,具有类似的术后维生素D结果.

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科学领域:

  • 腹腔外科手术是什么意思
  • 内分泌学 在内分泌学.
  • 营养科学 营养科学

背景情况:

  • 腹腔外科手术改变了胃肠道的吸收,可能会影响营养状况,特别是维生素D.
  • 了解不同减肥手术对维生素D和身体成分的影响,对于患者管理至关重要.

研究的目的:

  • 为了比较经过Roux-en-Y胃绕道 (RYGB) 和垂直袖子胃切除术 (VSG) 的患者之间的维生素D水平和身体组成.

主要方法:

  • 120名肥胖患者 (II/III类,18-65岁) 的回顾性队列研究,接受了VSG或RYGB.
  • 收集的数据包括人口统计数据,手术后的时间,肥胖指标,身体成分 (脂肪质量),体力活动和食物频率.
  • 分析了血清25-氧维生素D (25OHD) 和胰岛素变量.

主要成果:

  • 在VSG和RYGB组之间,身体组成或手术后维生素D水平没有显著差异.
  • 在类甲状腺激素 (PTH),总骨矿物密度 (BMD) 和胰岛素变量之间观察到显著的差异.
  • 组内分析显示,体质指数 (BMI) 和维生素D对VSG的显著变化,BMI对RYGB.

结论:

  • 无论是VSG还是RYGB都有效地减少脂肪质量.
  • 这些手术显示了与手术后维生素D水平相似的结果,在PTH,BMD和胰岛素中发现了差异.
  • 可能需要进一步的研究来充分阐明长期营养影响.