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在SLE中,sNASP突变通过TAK1通路加剧TLR4介导炎症

Yatao Bao1, Meng Lian1, Yong Chen1

  • 1School of Basic Medical Science, Weifang Medical University, Weifang 261053, China.

Journal of immunology research
|September 29, 2023
PubMed
概括

突变的体质核自身抗原性精子蛋白 (sNASP) 基因通过增强巨细胞中的Toll-like受体4 (TLR4) 信号传递来促进全身性红斑狼 (SLE). 这一发现揭示了自身免疫性疾病发展的关键机制.

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