出生缺陷的患病率和趋势 - - 中国山西省五个县,2003-2022年
Duoduo Wang1,2, Zhijiao Song3, Yali Zhang1,2
1Institute of Reproductive and Child Health / National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
China CDC weekly
|September 29, 2023
概括
西省在叶酸计划后,神经管缺陷 (NTDs) 减少. 然而,先天性心脏缺陷 (CHDs) 的增加,突出需要改进查和资源分配.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 儿科 儿科 儿科
背景情况:
- 中国的西省有出生缺陷 (BD) 的患病率最高.
- 2012-2017年,国家叶酸计划导致神经管缺陷 (NTD) 减少53.89%.
- 山西的先天性心脏缺陷 (CHD) 患病率显著增加,到2014年成为主要的BD.
研究的目的:
- 分析20多年来山西省出生缺陷 (BD) 患病率的趋势.
- 评估公共卫生倡议对NTD和CHD的影响.
- 确定公共卫生干预出生缺陷预防和管理的领域.
主要方法:
- 回溯分析来自山西省五个县的出生缺陷数据.
- 在20年的时间里,NTD,CHD和其他BD的流行率的比较.
- 评估影响检测率的诊断和医疗保健准入限制.
主要成果:
- 在过去二十年中,总体BD和NTD的显著减少.
- NTD仍然是最常见的BD (2017-2022年),而CHD已经上升到前五名,尽管低于全国平均水平.
- 高比例的外部异常;低估内部异常,如CHDs由于有限的医疗保健机会.
结论:
- 持续推广叶酸补充剂对于预防NTD至关重要.
- 建议加强医疗资源的分配,并为心血管疾病查和诊断提供当地培训.
- 解决医疗保健接入障碍对于山西精准的BD检测和管理至关重要.
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