后COVID-19胆血管病变:系统性审查
Mazen Abdalla Rasheed1, Vinícius Remus Ballotin2, Lucas Goldmann Bigarella2
1Acute Medicine, University of South Wales, Cardiff CF37 1DL, United Kingdom.
World journal of methodology
|September 29, 2023
概括
COVID-19可以引起二次硬化胆管炎 (SC),称为COVID-19后胆管病变. 这种严重的疾病需要进一步研究肝移植等治疗方法.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- COVID-19主要导致呼吸系统疾病,但也可能导致二次硬化胆管炎 (SC),称为COVID-19后胆管病变.
- 新出现的证据凸显了COVID-19引发这种严重肝病的可能性.
研究的目的:
- 综合现有的病例报告,评估当前对COVID-19后胆血管病变的理解.
- 巩固有关COVID-19这种新出现的并发症的知识.
主要方法:
- 在主要数据库 (Scopus,Web of Science,PubMed) 中使用医学主题标题和健康科学描述符进行全面的文献搜索.
- 包括英语,西班牙语或葡萄牙语的研究,以及手动查找参考清单.
- 描述性分析和参考引用分析用于数据总结和评估.
主要成果:
- 对63篇全篇文章的分析显示,大多数受影响的患者是男性,肝功能测试高 (93.8%).
- 图像检查显示管道变厚 (47.7%) 和肝内管道结晶 (45.7%);肝脏活检在74.4%的病例中证实了SC.
- 16名患者接受了肝移植,报告有3例成功结果.
结论:
- 后COVID-19胆血管病变是一个显著和日益关注的问题,特别是随着长期COVID综合征的增加.
- 肝移植是一种潜在的治疗方法,但进一步的研究对于确定其有效性和探索替代疗法至关重要.
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