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Updated: Jul 15, 2025

Single Particle Cryo-Electron Microscopy: From Sample to Structure
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Single Particle Cryo-Electron Microscopy: From Sample to Structure

Published on: May 29, 2021

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电子显微镜和个体粒子电子断层扫描揭示的高分辨率单分子结构

Lei Zhang1, Gang Ren1

  • 1The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, USA.

Journal of physical chemistry & biophysics
|September 29, 2023
PubMed
概括

研究人员捕获了第一个单个蛋白质的3D电子显微镜图像,揭示了它们的动态结构. 这一突破使得粒子对粒子的分析成为可能,进步了对蛋白质动态的研究.

关键词:
冷电子断层扫描 (CryoET) 是一种通过冷阳性染色 (Cryo-PS) 进行染色.电子显微镜 (EM) 的使用电子断层扫描 (ET) 是一种电子断层扫描.均衡的波动是平衡的波动.个人粒子电子断层扫描 (IPET)优化的负染色 (OpNS)蛋白质动力学 蛋白质动力学蛋白质结构 蛋白质结构单个分子结构的结构.

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