在ST升高心肌梗塞后的晚期左心室重塑后,早期左心室末期透析体积变化的预测值
Lei Yi1, Tianqi Zhu1, Xuezheng Qu1
1Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cardiology journal
|September 29, 2023
概括
心肌梗塞后左心室末端透缩体积 (LVEDV) 的早期变化预测了以后的重塑. 在出院和PCI后1个月监测LVEDV可以帮助识别患有左心室改造风险的患者.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 干预心脏病学 干预心脏病学
背景情况:
- 左心室重塑 (LVR) 是急性ST升高心肌梗塞 (STEMI) 后不良结果的关键预测因素.
- 初级穿皮冠状动脉干预 (PCI) 是STEMI的标准治疗方法.
- 了解LVR的早期指标对于患者管理至关重要.
研究的目的:
- 预期评估STEMI患者的LVR,这些患者接受了初级PCI治疗.
- 检查早期左心室扩张和晚期LVR之间的关系.
- 确定预测LVR的早期回声心脏学标志物.
主要方法:
- 连续301名接受初级PCI的STEMI患者被纳入.
- 序列心声扫描在多个时间点进行:PCI后的第一天,出院,1个月和6个月.
- 分析了左心室末端透支体积 (LVEDV) 的变化.
主要成果:
- 左心室重塑 (LVR) 在18.9%的患者中发生.
- 在LVR组中,LVEDV从第一天到离院期间下降,与非LVR组相反.
- 退院和PCI后1个月LVEDV的早期变化准确地预测了晚期LVR (AUC = 0.80).
结论:
- 出院时的LVEDV降低和1个月后的LVEDV增加都与6个月后的晚期LVR有关.
- 早期全面监测LVEDV变化对于预测LVR至关重要.
- 这些发现支持在STEMI患者的风险分层中使用串行心声回声学.
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