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FLOT1在人类疾病中的作用 (综述)

Ziqing Zhan¹, Meng Ye¹, Xiaofeng Jin¹

¹Department of Oncology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315020, P.R. China.

Molecular medicine reports

|September 29, 2023

概括

浮提林-1 (FLOT1) 蛋白质在细胞过程和疾病中发挥着多种作用. FLOT1既能促进癌症,又能抑制癌症,其失调与神经系统和其他疾病有关.

科学领域:

分子生物学分子生物学
细胞生物学细胞生物学
生物化学生物化学

背景情况:

林-1 (FLOT1) 是脂质的支架蛋白,参与内细胞和突触形成.
FLOT1在癌症中表现出上下文依赖的作用,既起瘤促进作用,又起瘤抑制作用.
FLOT1失调与各种疾病有关,包括神经系统疾病,心血管疾病和糖尿病.

结论:

FLOT1是各种生物过程和人类疾病的关键调节者.
准FLOT1为各种癌症和神经系统疾病提供了一个有前途的治疗策略.

关键词:

细胞内分泌症 (endocytosis) 发生在细胞内.提林蛋白质 1 1 的蛋白质.脂质漂浮艇是什么意思脂质漂浮艇监管监管监管监管监管监管瘤发生的起源

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